Causes of Male Infertility


Dr. Roger Lobo, of the American Society for Reproductive Medicine explains the causes of male infertility.

Causes of Male Infertility

Transcript

Dr. Roger Lobo, of the American Society for Reproductive Medicine explains the causes of male infertility.

Hi I'm Dr. Roger Lobo with the American Society for Reproductive Medicine.

Today, we're talking about the causes of male infertility. Male infertility can be due to a variety of conditions. Some of these can be found and corrected while others cannot be corrected.

Most problems with male infertility occur when there are low numbers of sperm or abnormalities in their movement or shape. This can result from abnormalities in the production, transport,  or delivery of sperm.

A varicocele is a common potentially correctable cause of male infertility.   A varicocele is a collection of enlarged veins in the scrotum that can affect sperm production and its characteristics. Varicocele occurs in about 15% of all men and as many as 40% of those who are infertile. The tricky thing with that area is there are a lot of fertile men who are found with varicocele, so what do you do when you find a small one in an infertile male? This is when a male might first want to consult with a urologist before acting on taking care of a varicocele which sometimes might require surgery.

About 10 to 15% of men with low sperm counts have an abnormality in the Y chromosome which affects the development of sperm. Others may be born without critical parts of the sperm transport process, such as the vas deferens, which connect the testes to the male urethra.

Vasectomy is a common surgical cause of male infertility in men who have changed their minds about fertilization.   But men who have had other surgery in or near the reproductive tract also can have problems. Injury to the nerve supply and/or obstructions in a transport system can affect sperm production.  

For some men, fertility is affected by abnormal hormones, too. Too much estrogen and/or too little testosterone can negatively affect the development and maturation of sperm. Other hormones may be involved as well.

Temperature also plays a critical role. Sperm can only mature at temperatures lower than the core body temperature.  This is why the testes normally lie in the scrotal sacs outside of the body. Heat exposure or conditions where the testes have not descended into the scrotum can affect sperm production. 

Male infertility can also be due to infections,   certain medical conditions, and exposure to toxins such as chemotherapy or radiation.

To learn more, check out our other videos on fertility, including the Basic Infertility Evaluation.

Videos

Resources For You

The American Society for Reproductive Medicine (ASRM) is committed to providing patients with the highest quality information about reproductive care.

Infertility

Podcast Icon

SART Fertility Experts - Environmental Impacts on Fertility

In this episode, the fertility experts discuss the impact of the environment, including air, climate, and chemical exposures on infertility.   Listen to the Episode
PR Bulletin Icon

Survey shows strong support for increased access to fertility treatments

A new public opinion poll reveals strong support for improved access to In Vitro Fertilization (IVF). 

View the Press Release
News Icon

Leave Your Mark! NIAW April 21-27

National Infertility Awareness Week Action Round-Up Click here to leave your mark during NIAW2024
PR Bulletin Icon

National Infertility Awareness Week 2024: Leave Your Mark

Next week is National Infertility Awareness Week, a federally recognized health observance founded to increase awareness of infertility.

View the Press Release
Announcement Icon

ASRM reacts to Alabama legislation

We are pleased that the legislation passed into law by the Alabama General Assembly will at least allow our members in the state to care for their patients.

View the Press Release
Announcement Icon

IVF at the SOTU: Fertility care expected to be major focus at State of the Union

Protecting access to IVF care is expected to be a major theme of the State of the Union on Thursday.

View the Press Release
Announcement Icon

ASRM Responds to Proposed Alabama Legislation

We are proud of our Alabama members and their patients, who have been such incredible advocates working to motivate their legislators to protect IVF.

View the Press Release
Announcement Icon

Senate Budget Hearing is Well Timed Following Alabama IVF Ruling

ASRM statement regarding the Senate Budget Committee’s hearing entitled: No Rights to Speak of: The Economic Harms of Restricting Reproductive Freedom.

View the Press Release
Announcement Icon

ASRM Responds to Senate’s Failure to Pass Access to Family Building Act

We are disappointed by the Senate’s failure to meet the moment and pass federal legislation protecting access to in vitro fertilization (IVF).

View the Press Release
PR Bulletin Icon

Society of Reproductive Biologists and Technologists (SRBT) Condemns Recent Court Decision in Alabama

The recent ruling by the Alabama Supreme Court that frozen embryos are legally considered people has sparked controversy and concern.

View the Press Release
Announcement Icon

ASRM Condemns Profoundly Misguided and Dangerous Court Decision in Alabama

In LePage v Mobile Infirmary Clinic, the Alabama Supreme Court made a decision that flies in the face of medical reality and the needs of the citizens.

View the Press Release
Podcast Icon

SART Fertility Experts - Recurrent Pregnancy Loss and Implantation Failure

"I can get pregnant, but I can't stay pregnant," is echoed by patients with recurrent pregnancy loss.   Listen to the Episode
Podcast Icon

SART Fertility Experts - Wellness and Fertility: Diet, Sleep and Exercise

Drs. Timothy Hickman and Rashmi Kudesia discuss the links between lifestyle and fertility. Listen to the Episode
Podcast Icon

SART Fertility Experts - Navigating IVF as a Couple

Mary Casey Jacob, PhD is interviewed by Dr. Daniel Grow, and together they explore the emotional and practical support that couples need. Listen to the Episode
Patient Ed Icon

Male Fertility Journey

About 20% of infertility cases are due to a male factor alone. Another 30% involves both male and female factors.

View the Patient Journey
Patient Ed Icon

Female Fertility Journey

If you've been trying to get pregnant for more than a year, you may have infertility. Infertility is a disease of the reproductive system that impairs one of the body's most basic functions: the conception of children.

View the Patient Journey
Podcast Icon

SART Fertility Experts - Endometriosis

Endometriosis is a condition that can affect many facets of a person’s life, from pelvic pain to struggles with infertility.   Listen to the Episode
Podcast Icon

SART Fertility Experts - Recurrent Pregnancy Loss

Candace discusses her experience with infertility, IVF, multiple pregnancy losses and ultimately a successful delivery with Dr. Julia Woodward.
Listen to the Episode
Podcast Icon

SART Fertility Experts - Financial Aspects of Infertility Treatment

“I know what treatment I want and need to do, but how can I afford it?”  This is a common question infertility patients often ask themselves. Listen to the Episode
Podcast Icon

SART Fertility Experts - Infertility Advocacy and Government Affairs

In today's episode, Dr. Mark Trolice interviews Sean Tipton about the fact that many infertility patients do not have insurance coverage for treatment. Listen to the Episode
Podcast Icon

SART Fertility Experts - Your Infertility Nurse: Partner in Your Care

Infertility nurse practitioner and health coach Monica Moore explains the essential role of the infertility nurse in the IVF process.  Listen to the Episode
Podcast Icon

SART Fertility Experts - IVF: Cycles of Hope and Heartbreak

Does stress cause infertility or is it the other way round?  Listen to the Episode
Podcast Icon

SART Fertility Experts - RESOLVE and Infertility

Due to the unique stress of infertility, patients often look for resources and support in addition to those provided by their medical provider. Listen to the Episode
Podcast Icon

SART Fertility Experts - Safe Surfing: The Pros and Perils of Social Media

Dr. Kenan Omurtag, MD joins host Dr. Mark Trolice to discuss the use of social media in the field of infertility.  Listen to the Episode
Podcast Icon

SART Fertility Experts - What is an REI?

These experts in infertility lead IVF programs, perform reproductive surgery, and perform research to enhance the field of reproductive medicine. Listen to the Episode
Patient Ed Icon

Infertility: an Overview (booklet)

Infertility is typically defined as the inability to achieve pregnancy after one year of unprotected intercourse. View the booklet
Patient Ed Icon

Optimizing Natural Fertility

Before attempting pregnancy, a woman should make sure she is healthy enough for pregnancy by adopting a healthier lifestyle and taking prenatal vitamins. If she has a medical or genetic condition or risk of one, she should seek advice from a medical professional before conceiving (becoming pregnant) View the fact sheet
Patient Ed Icon

Optimizing Male Fertility

About 20% of infertility cases are due to a male factor alone. Another 30% involves both male and female factors. View the fact sheet
Videos Icon

Male Fertility and Infertility - a patient education video

Male Factor Infertility is responsible for about 30% of infertility cases and can contribute infertility to an additional 20% of cases. Watch Video
Videos Icon

Infertility

Infertility is the result of a disease (an interruption, cessation, or disorder of body functions, systems, or organs) of the male or female reproductive tract which prevents the conception of a child or the ability to carry a pregnancy to delivery.  Watch Video
Videos Icon

Basic Infertility Evaluation

Dr. Roger Lobo of the American Society for Reproductive Medicine discusses the various methods to evaluate infertility. Watch Video
Videos Icon

Fibroid Tumors

An educational video that answers patient questions about the causes, symptoms, diagnosis and management of uterine fibroids. Watch Video
Videos Icon

Infertility Treatments

Dr. Roger Lobo of the American Society for Reproductive Medicine discusses the various treatments for infertility. Watch Video
Videos Icon

Understanding Fertility

In this video series, Dr. Roger Lobo explains the basics of infertility, including causes, treatments and coping methods. Watch Video
Videos Icon

Surviving the Roller Coaster Emotions of Infertility Treatment

The experience of infertility is a rollercoaster of hope and disappointment. Treatment presents an opportunity for hope as well as a new set of challenges. Watch Video
Patient Ed Icon

Age and Fertility (booklet)

Generally, reproductive potential decreases as women get older, and fertility can be expected to end 5 to 10 years before menopause. View the Booklet
Patient Ed Icon

What is Recurrent Pregnancy Loss (RPL)?

This is a condition when a woman has 2 or more clinical pregnancy losses (miscarriages) before the pregnancies reach 20 weeks. View the fact sheet
Patient Ed Icon

Endometriosis: Does It Cause Infertility?

When tissue like the tissue that normally lines the inside of the uterus (endometrium) is found outside the uterus, it is termed “endometriosis.” View the Fact Sheet
Patient Ed Icon

What is Premature Ovarian Insufficiency (Also Called Premature Ovarian Failure)?

When a woman’s ovaries stop working before age 40, she is said to have premature ovarian insufficiency (POI).  View the fact sheet
Patient Ed Icon

What is intracytoplasmic sperm injection (ICSI)?

A procedure called intracytoplasmic sperm injection (ICSI) can be done along with in vitro fertilization (IVF) if a sperm cannot penetrate the outer layer of an egg. Read the Fact Sheet
Patient Ed Icon

Acupuncture and Infertility Treatment

Acupuncture is an alternative medical treatment that involves placing very thin needles at different points on the body. View the Fact Sheet
Patient Ed Icon

Male infertility evaluation: what do I need to know?

Infertility is the inability to achieve pregnancy after one year of unprotected sex. View the fact sheet
Patient Ed Icon

Saline infusion sonohysterogram (SHG)

Saline infusion sonohysterography (SIS or SHG) is aprocedure to evaluate the uterus and the shape of the uterine cavity. View the fact sheet
Patient Ed Icon

Sexual dysfunction and infertility

Sexual dysfunction is a problem in a person’s sexual desire, arousal, or orgasm. View the fact sheet
Patient Ed Icon

Testosterone use and male infertility

Testosterone (also referred to as “T”) is a hormone produced in men by the testes (testicles). View the fact sheet
Patient Ed Icon

What are fibroids?

Uterine fibroids (also called myomas or leiomyomas) are benign (noncancerous) tumors of muscle tissue found in the uterus. View the fact sheet
Patient Ed Icon

What is In Vitro Maturation (IVM)?

In vitro maturation (IVM) is when a woman’s eggs are collected and matured outside the body. This is done as part of an in vitro fertilization (IVF) procedure. View the fact sheet
Patient Ed Icon

Stress and infertility

It is not clear how exactly stress impacts fertility. Read the Fact Sheet
Patient Ed Icon

Hyperprolactinemia (High Prolactin Levels)

Prolactin is a hormone produced by your pituitary gland which sits at the bottom of the brain. Read the fact sheet
Patient Ed Icon

Defining Infertility

Infertility is “the inability to conceive after 12 months of unprotected intercourse.” View the Fact Sheet
Patient Ed Icon

Fertility Rights and Responsibilities

Can a fertility program or clinic deny treatment to patient(s) if there is concern about the ability to care for the child(ren)? Yes. Fertility programs can withhold services if there are signs that patients will not be able to care for child(ren). View this Fact Sheet
Patient Ed Icon

Smoking and infertility

Most people understand that smoking increases the risk for heart, vascular, and lung disease. View the fact sheet
Patient Ed Icon

Infertility Counseling and Support: When and Where to Find It

Infertility is a medical condition that touches all aspects of your life. View the fact sheet
Videos Icon

Coping With Infertility

Dr. Roger Lobo of the American Society for Reproductive Medicine discusses various methods of coping with infertility. Watch Video
Videos Icon

Endometriosis

Endometriosis is a condition in which endometrial tissue, which normally lines the uterus, develops outside of the uterine cavity in abnormal locations. Watch Video
Videos Icon

Causes of Female Infertility

Dr. Roger Lobo, of the American Society for Reproductive Medicine explains the causes of female infertility. Watch Video
Patient Ed Icon

Diagnostic Testing for Male Factor Infertility

When a couple has trouble having a baby, there's about a 50-50 chance that the man has a problem contributing to the pregnancy.

  View the Fact Sheet
Info Icon

FAQ About Infertility

Infertility is not an inconvenience; it's a disease of the reproductive system that impairs the body's ability to perform the basic function of reproduction. Learn the facts
Info Icon

FAQ About the Psychological Component of Infertility

Infertility often creates one of the most distressing life crises that a couple has ever experienced together. Learn the facts
Patient Ed Icon

Mary Dolan's Story

I was diagnosed with diminished ovarian reserve/premature ovarian failure at 28 years old.
Read the story
Infographic Icon

Infertility Infographics

ASRM has prepared infographics to illustrate the subject of Infertility better. View the infographics

Male Fertility/Andrology

Podcast Icon

SART Fertility Experts - Wellness and Fertility: Diet, Sleep and Exercise

Drs. Timothy Hickman and Rashmi Kudesia discuss the links between lifestyle and fertility. Listen to the Episode
Patient Ed Icon

Male Fertility Journey

About 20% of infertility cases are due to a male factor alone. Another 30% involves both male and female factors.

View the Patient Journey
Podcast Icon

SART Fertility Experts - Urology and Male Reproductive Health

Male infertility is less often discussed than female infertility. Dr. Ajay Nangia discusses when a man should seek help with conceiving.
Listen to the Episode
Podcast Icon

SART Fertility Experts - Male Factor

Infertility is not just a female problem. Dan candidly shares his journey with both diagnosis and treatment of male infertility with Dr. Paul Lin.
Listen to the Episode
Podcast Icon

SART Fertility Experts - IVF: Cycles of Hope and Heartbreak

Does stress cause infertility or is it the other way round?  Listen to the Episode
Podcast Icon

SART Fertility Experts - Male Fertility

Did you know that up to 40% of infertile couples suffer from male factor infertility? Listen to the Episode
Patient Ed Icon

Infertility: an Overview (booklet)

Infertility is typically defined as the inability to achieve pregnancy after one year of unprotected intercourse. View the booklet
Patient Ed Icon

Optimizing Natural Fertility

Before attempting pregnancy, a woman should make sure she is healthy enough for pregnancy by adopting a healthier lifestyle and taking prenatal vitamins. If she has a medical or genetic condition or risk of one, she should seek advice from a medical professional before conceiving (becoming pregnant) View the fact sheet
Patient Ed Icon

Optimizing Male Fertility

About 20% of infertility cases are due to a male factor alone. Another 30% involves both male and female factors. View the fact sheet
Videos Icon

Male Fertility and Infertility - a patient education video

Male Factor Infertility is responsible for about 30% of infertility cases and can contribute infertility to an additional 20% of cases. Watch Video
Videos Icon

Infertility

Infertility is the result of a disease (an interruption, cessation, or disorder of body functions, systems, or organs) of the male or female reproductive tract which prevents the conception of a child or the ability to carry a pregnancy to delivery.  Watch Video
Videos Icon

Basic Infertility Evaluation

Dr. Roger Lobo of the American Society for Reproductive Medicine discusses the various methods to evaluate infertility. Watch Video
Videos Icon

Infertility Treatments

Dr. Roger Lobo of the American Society for Reproductive Medicine discusses the various treatments for infertility. Watch Video
Videos Icon

Understanding Fertility

In this video series, Dr. Roger Lobo explains the basics of infertility, including causes, treatments and coping methods. Watch Video
Videos Icon

Surviving the Roller Coaster Emotions of Infertility Treatment

The experience of infertility is a rollercoaster of hope and disappointment. Treatment presents an opportunity for hope as well as a new set of challenges. Watch Video
Patient Ed Icon

What is intracytoplasmic sperm injection (ICSI)?

A procedure called intracytoplasmic sperm injection (ICSI) can be done along with in vitro fertilization (IVF) if a sperm cannot penetrate the outer layer of an egg. Read the Fact Sheet
Patient Ed Icon

Male cancer, cryopreservation, and fertility

This can be confusing since the terms are often used interchangeably in the media and casual conversation. View the fact sheet
Patient Ed Icon

Male infertility evaluation: what do I need to know?

Infertility is the inability to achieve pregnancy after one year of unprotected sex. View the fact sheet
Patient Ed Icon

Surgical techniques for sperm retrieval: what should I know?

As many as 10% to 15% of infertile men have no sperm in their ejaculate (the fluid released from the penis during orgasm). View the fact sheet
Patient Ed Icon

Testosterone use and male infertility

Testosterone (also referred to as “T”) is a hormone produced in men by the testes (testicles). View the fact sheet
Patient Ed Icon

Weight and fertility

One of the easiest ways to determine if you are underweight or overweight is to calculate your body mass index (BMI). View the fact sheet
Patient Ed Icon

Stress and infertility

It is not clear how exactly stress impacts fertility. Read the Fact Sheet
Patient Ed Icon

Sperm morphology (shape): Does it affect fertility?

The most common test of a man’s fertility is a semen analysis. View the fact sheet
Patient Ed Icon

Spinal cord injury sperm retrieval

There are several reasons a man with a spinal cord injury (SCI) might have infertility. View the fact sheet
Patient Ed Icon

Varicocele

A varicocele is a variation of normal anatomy in which veins in the scrotum (the sac that holds the testicles) become enlarged and sometimes even visible. View the fact sheet
Patient Ed Icon

Fertility Options After Vasectomy

Vasectomy is currently one of the most common methods of sterilization in the United States. After your vasectomy, if you change your mind about having children, there are two procedures that can help you have a child with your partner. View the Fact Sheet
Patient Ed Icon

Diagnostic Testing for Male Factor Infertility

When a couple has trouble having a baby, there's about a 50-50 chance that the man has a problem contributing to the pregnancy.

  View the Fact Sheet
Info Icon

FAQ About Infertility

Infertility is not an inconvenience; it's a disease of the reproductive system that impairs the body's ability to perform the basic function of reproduction. Learn the facts
Infographic Icon

Male Fertility Infographics

ASRM has prepared infographics to illustrate the subject of  Male Fertility better. View the infographics

Find a Health Professional

Connect with reproductive medicine experts who will guide you through your unique journey. Our search tool allows personalized matches based on location, specialization, and expertise. Take control of your reproductive health with compassionate providers, innovative treatments, and unwavering support.
Search for an Expert
Healthcare professional eager to help a patient