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Screening for Latent and Genital Tuberculosis in the Infertility Clinic: An Opportunity to Improve Patient Health and Outcomes

HIGHLIGHTS FROM THE AMERICAN SOCIETY FOR REPRODUCTIVE MEDICINE’S 2017 SCIENTIFIC CONGRESS & EXPO

Note: Press room open Sun. October 29th, 2pm-5pm CDT; Mon. October 30 -Wed. November 1, 8:00am-5:30pm CDT. 210-582-7029

San Antonio, TX- Today at the Scientific Congress and Expo of the American Society for Reproductive Medicine, doctors from the Yale School of Medicine and Yale-New Haven Hospital presented the findings from their investigation into the prevalence of female genital tuberculosis (FGTB) in the United States.

Having observed an increase in reports of complications to mothers and newborns resulting from FGTB after fertility treatments, particularly IVF, the researchers conducted a prospective cohort study using WHO screening guidelines at their fertility center.  From January 2014 to January 2017 all patients evaluated for infertility were examined for TB risk factors. Those found to be at risk were given a blood test for TB. Patients whose blood tested positive were tested further for FGTB with endometrial biopsy followed by endometrial TB-PCR and acid-fast culture, and they received a detailed chart review.

Of the 326 patients identified as being at risk by the WHO guidelines, 25 had a positive blood test for latent TB. Slightly more than half these patients (14/25) were originally from areas where tuberculosis is endemic. One patient of the 25 had evidence of FGTB in her endometrial biopsy, positive TB-PCR, and a positive culture. 

ASRM President Richard J. Paulson, MD commented, “Genital tuberculosis often results in infertility and can lead to poor outcomes for mother and baby if an infected woman becomes pregnant. With increased immigration to the US from areas where TB is endemic, screening for the disease in fertility patients is an opportunity to improve their overall health and head off obstetrical complications. We hope the WHO TB screening becomes more widely used.”

P-27 Tal et al,” LATENT AND GENITAL TUBERCULOSIS IN THE INFERTILE POPULATION IN US - EXPERIENCE AT AN ACADEMIC FERTILITY CENTER IN THE NORTHEAST UNDERSCORES A NEED FOR VIGILANCE”

 

ASRM is a multidisciplinary organization dedicated to the advancement of the science and practice of reproductive medicine. The Society accomplishes its mission through the pursuit of excellence in education and research and through advocacy on behalf of patients, physicians, and affiliated health care providers. The Society is committed to facilitating and sponsoring educational activities for the lay public and continuing medical education activities for professionals who are engaged in the practice of and research in reproductive medicine. www.asrm.org 


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