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Enzymatic Biofuel Creates Nanoscale Electric Current to Improve Sperm Motility

HIGHLIGHTS FROM THE AMERICAN SOCIETY FOR REPRODUCTIVE MEDICINE’S 2017 SCIENTIFIC CONGRESS & EXPO

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San Antonio, TX-  Today, at the Scientific Congress and Expo of the American Society for Reproductive Medicine, researchers from the CHA Fertility Centers and Biomedical Sciences of CHA University, Seoul, Republic of Korea presented the results of their work to improve sperm motility using an enzymatic biofuel cell generating nanoscale electrical stimulation. 

Normal semen samples evaluated for motility, viability, acrosome reaction, and mitochondrial function were incubated in culture dishes equipped with anodic and cathodic compartments containing enzyme catalysts, which created an electric current within the dish. Exposed to low levels of current- optimally 110 nanoAmps and 256 nanoAmps per square centimeter- sperm motility was enhanced by as much as 30% to 40%, with the motility of sperm from the anodic side of the dish improving slightly more than that of sperm from the cathodic side. At higher measured current levels (1 microAmp) sperm did not survive. Optimal electrical stimulation enhanced mitochondrial activity, but had no effect on the acrosome reaction.

ASRM Vice President Peter Schlegel, MD remarked, “This novel use of bioelectric stimulation may prove to be a useful enhancement to sperm preparation for artificial insemination when sperm motility needs a boost.”

O-197  T. Shin et al, NANOSCALE ELECTRICAL STIMULATION OF THE ENZYMATIC BIOFUEL CELL PROMOTE MOTILITY OF THE HUMAN SPERMATOZOA 

 

 

ASRM is a multidisciplinary organization dedicated to the advancement of the science and practice of reproductive medicine. The Society accomplishes its mission through the pursuit of excellence in education and research and through advocacy on behalf of patients, physicians, and affiliated health care providers. The Society is committed to facilitating and sponsoring educational activities for the lay public and continuing medical education activities for professionals who are engaged in the practice of and research in reproductive medicine. www.asrm.org 


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